Leber’s Hereditary Optic Neuropathy (LHON) symptoms usually begin as sudden, painless loss of central vision. The classic pattern is for one eye to suddenly lose central vision, then on average 8 weeks later the other eye also loses central vision, though many variations on this pattern are possible.
LHON is a genetic disorder that can cause the optic nerve to atrophy but does not always do so. It is the most common mitochondrial disease. A woman carrying a LHON mutation will pass it to all of her children; men with the LHON gene never pass it to their children. Those who have lost their central vision due to LHON are referred to as “affected;” those with a LHON mutation gene but without vision loss are “carriers.”
What Is LHON?
What Causes LHON?
Because there is a clear pattern of LHON inheritance, those with a family member on the maternal inheritance chain with LHON should expect that any sudden, painless central vision loss is caused by LHON. However, carrying the LHON mutation does not mean that a LHON carrier will lose central vision; most who carry the mutation do not.
"Our goal is for people with disabilities and diseases to no longer forgo on experiences in life, help me make a difference because
I lost my sight - not my vision"
- Joseph Sehwani, Founder of Dreamscape Foundation
Help support LHON by assisting the Dreamscape Foundation. With your help and donations we will be able to accomodate individuals impacted by LHON and cater to their day to day activites. Together we can turn our dream into reality.
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